Prof. John Kanis


Professor Kanis is a founding member and honorary President of the IOF as well as editor of Osteoporosis International. He is currently Emeritus Professor in Human Metabolism and the Director of the WHO Collaborating Centre for Metabolic Bone Diseases at the University of Sheffield. Author of more than 800 papers, chapters and books on bone disease and metabolism, Professor Kanis has received numerous awards and honours, including the ASBMR Bartter Award for Clinical Science, the John B. Johnson Award of the Paget Disease Foundation (USA), and a Doctorate Honoris Causa from the Sahlgrenska Academy, University of Gothenburg. Prof. Kanis is the author of more than 800 papers, chapters and books on bone disease and metabolism.

The WHO diagnostic criteria for osteoporosis were first established in 1994 under the chairmanship of John Kanis. His own work in the field ranges from basic bone physiology research to the epidemiology of fractures. For the last ten years he has led an international research team commissioned by the WHO to develop a model for calculating absolute fracture risk, FRAX.


Prof. Eugene V McCloskey


Eugene McCloskey is a Professor in Adult Bone Disease, University of Sheffield, Sheffield, UK.
Prof. McCloskey has been the principal investigator in a large number of Medical Research Council and pharmaceutical industry-funded studies. He is an acknowledged expert in the fields of vertebral fracture definition and epidemiology, as well as non-invasive assessments of bone strength and fracture risk. He contributed to the development of the FRAX tool for estimating fracture risk and to the National Osteoporosis Guidance Group. Dr. McCloskey is secretary of the BRS Board, chairs the ASBMR Ancillary Program Committee and is a member of the National Specialty Group for Musculoskeletal Diseases. He has published over 150 peer-reviewed articles, book chapters, guidelines and reviews.


As DO-HEALTH partners, Profs Kanis and McCloskey investigate the contribution of fall risk to absolute fracture risk within the FRAX model.