DO-HEALTH central laboratory
All biomarkers of the organ-specific biomarker study assessed in all 2157 DO-HEALTH participants at baseline, 12, 24 and 36 months will be quantified in the central DO-HEALTH laboratory at the University of Zurich (Institute of Clinical Chemistry, University Hospital Zurich, headed by Arnold von Eckardstein). This laboratory is accredited according to ISO/IEC 17025. All clinical chemistry tests and immunoassays for the organ-specific biomarker study are provided by the DO-HEALTH industry partner Roche-diagnostics free of charge and performed on a COBAS8000 auto-analyser.
Prof. Arnold von Eckardstein
Prof. A. von Eckardstein is the Chair of the Institute of Clinical Chemistry at the University of Zurich is an experienced participant and coordinator of European biomarker research projects, e.g. “HDLomics in FP6”. His research interests include risk factors, biomarkers and pathogenesis of vascular disease; regulation and function of lipoproteins, especially high density lipoproteins (HDL); lipid metabolism and lipidomics. He has published about 250 original and review papers in international scientific journals. Prof. von Eckardstein is the past Chairman of the European Lipoprotein Club and current Chairman of the Executive Committee of the Swiss Working Group on Lipids and Atherosclerosis. He is the past President of the German Society of Arteriosclerosis Research and of the Swiss Society of Clinical Chemistry. He has served as vice-president of International Task Force for the Prevention of Coronary Heart Disease. He is a fellow of the American Heart Association (FAHA; Council on Arteriosclerosis, Thrombosis and Vascular Biology) and a distinguished Fellow of the International Atherosclerosis Society.